Easy Reefs - DKI 1.3 B-glucan - 50 g - Immunostimulant pellets

The diatom Phaeodactylum tricornutum is characterized by its high content of bioactive molecules such as the omega-3 fatty acid EPA, the carotenoid pigment fucoxanthin and chrysolaminarin, a β-(1,3)-linked glucose monomer. water have limited β-(1,6) branching.

Among the known immunostimulating effects of a fish diet rich in Phaeodactylum tricornutum, it is worth highlighting:

• Increased activity of hemolytic complement.
• Stimulates phagocytic activity and respiratory activity of head kidney leukocytes
• Elevated serum levels of IgM, the major adaptive humoral response, are often the only class of immunoglobulins described in fish.
• Increased expression of IL-8, a pro-inflammatory cytokine that contributes (in conjunction with IL-1 and TNFα) to host defense mechanisms in response to invasion or colonization bacterial.

Additionally, chrysolaminarin-rich extracts have been shown to:

• stimulate the expression of the hsp90aa chaperones and the antimicrobial peptide hamp1, thus modulating the NF-κB pathway and the production of pro-inflammatory cytokines in macrophages,
• modulate key immune factor genes, such as glucan receptor c-type lectin (clec), interferon-related factors irf3 and irf7, TNFα, chemokine cxc10, g-type lysozyme, cd4 and IL-1β, support immunomodulatory and anti-inflammatory effects
• modulation of the intestinal microbiota by reducing bacteria of the genus Vibrio.